Decentralized Clinical Trial Platform – Remote & Hybrid Trials Made Easy

Built for researchers. Built for patients. Built to scale.

Castor’s suite of decentralized research tools is adaptable whether you’re just starting your journey into hybrid trials or you are ready to fully dive into decentralization.

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The Castor difference

Why choose Castor for decentralized clinical trials?

Castor is one of the few decentralized clinical trial platforms that combines EDC, ePRO, eCOA, eConsent and eRecruitment natively, with no middleware required. This gives teams a single validated system for all trial data, simplified regulatory submissions and lower total cost of ownership.

Unlike point solutions that require complex integrations, Castor gives sponsors, biotech companies and academic researchers a unified data environment from enrollment to lock. Trusted by 50,000+ researchers across academic, biotech and pharma settings worldwide.

50,000+

Researchers worldwide

90+

Countries supported

5-in-1

EDC, ePRO, eCOA, eConsent and eRecruitment in one platform

21 CFR Part 11

Regulatory compliant, GCP-aligned

 

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Flexible tech for modern clinical trial needs

Castor’s decentralized clinical trials platform enables you with unparalleled control. Each DCT module can be used alone or together, enabling you to plug-and-play with each tool, build a foundation of technology that can flex to meet your unique study needs, and scale at your own pace. Whether you’re running decentralized clinical trials, hybrid studies, or fully remote research.

Simplifying clinical research for you and the patient

Build clinical trials that are more efficient and more engaging for your participants with automated recruitment and enrollment, a native ePRO app for simplified data collection, and an intuitive interface with built-in video capability.

 

modular DCT components

 

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High quality, centralized data collection that makes sense for you

With Castor, you can always feel empowered to design a DCT workflow that’s flexible  and right for your trial, while never losing confidence in the strength of your data. Our open API gives customers the freedom to work with other platforms and data in their clinical trial ecosystem, integrating data from all sources and standardizing them for clinical relevance.

 

Success story

Launching a successful COVID-19 study with Castor’s DCT platform

World’s first study to use machine learning in diagnosis of COVID-19, supported by TAKEDA and Julius Clinical

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“Using Castor, we succeeded in recruiting over 17,824 patients enrolled in 15 weeks during a global pandemic, an achievement that could not have been accomplished without tools purpose-built with decentralized trials in mind.”

Marcel Van Willigen
Julius Clinical

 

Why decentralized clinical trials improve research outcomes

Decentralized clinical trials remove the barriers between patients and research. When participants can engage from home, trials become more accessible, more representative and more operationally efficient.

Faster patient recruitment

Remove geographic barriers and reach eligible participants across wider populations. Decentralized clinical trials consistently report faster enrollment versus traditional site-based studies.

Higher patient retention rates

Patients who participate from home are significantly less likely to withdraw. Fewer missed visits, lower dropout rates and more complete datasets improve the quality of your results.

Better real-world data capture

Collect continuous, ecological data from patients in their natural environment. Remote data capture surfaces outcomes that in-clinic visits miss and supports more representative datasets.

Reduced site burden and costs

Cut monitoring travel, paper handling and manual data reconciliation. Decentralized clinical trials reduce per-patient operational costs without compromising data quality or regulatory compliance.

Improved protocol compliance

Automated visit reminders, digital questionnaires and real-time compliance monitoring keep participants on schedule and reduce protocol deviations across your study population.

 

Trial design guide

Decentralized, hybrid and traditional trials: what is the difference?

Not all trial designs work for every protocol. Understanding the structure of decentralized, hybrid and traditional clinical trials helps sponsors choose the right model for their patient population and data requirements.

Feature Decentralized clinical trial Castor-powered Hybrid clinical trial Traditional trial
Patient location Remote, home-based or local pharmacy/clinic Mix of home and investigative site On-site at investigative site only
Visit structure All visits virtual via app or portal Some virtual, some in-person All visits in-person
Data collection ePRO, eCOA, EDC via app or web portal Digital tools and site-based EDC Site-based EDC or paper
Cost profile Lower per-patient costs, reduced monitoring burden Moderate costs Higher per-patient costs and site monitoring overhead
Best suited for Chronic conditions, large geographic catchment, patient-centric endpoints Protocols requiring some procedures on-site Complex interventions, device trials, procedures requiring clinical setting
Castor support ✓ Full platform support ✓ Full platform support ✓ Full platform support

 

FAQs

Frequently asked questions about decentralized clinical trials

Answers to the most common questions about decentralized clinical trial design, technology and how Castor supports your study from setup to lock.

What is a decentralized clinical trial (DCT)?
A decentralized clinical trial (DCT) is a study in which some or all trial activities are conducted remotely, at the patient’s home or a local facility, rather than at a central investigative site. Decentralized clinical trials use digital tools including ePRO, eConsent, eCOA and telemedicine to collect data without requiring patients to travel. The approach increases accessibility, reduces patient burden and can accelerate recruitment and retention across larger patient populations.
What is the difference between decentralized and hybrid clinical trials?
A fully decentralized clinical trial conducts all activities remotely using digital tools and local services. A hybrid clinical trial combines remote participation with some in-person site visits. Hybrid trials are common when certain procedures, assessments or regulatory requirements cannot be performed outside a clinical setting. Castor supports both decentralized and hybrid trial models within the same integrated platform.
What technology do decentralized clinical trials need?
Decentralized clinical trials typically require electronic data capture (EDC), electronic patient-reported outcomes (ePRO), electronic clinical outcome assessments (eCOA), electronic informed consent (eConsent) and patient recruitment tools. Castor integrates all of these capabilities into a single platform, removing the need for multiple vendors and complex data integrations between systems.
Why choose Castor for decentralized clinical trials?
Castor is one of the few platforms that combines EDC, ePRO, eCOA, eConsent and eRecruitment natively, with no middleware required. This gives teams a single validated system for all trial data, simplified regulatory submissions and lower total cost of ownership. Castor is trusted by 50,000+ researchers and is 21 CFR Part 11 and GCP compliant.
How do you recruit patients for decentralized clinical trials?
Castor’s eRecruitment module helps sponsors and sites identify, screen and enroll eligible patients using online screening forms, automated eligibility checks and integrated participant communication tools. By removing geographic barriers, Castor’s patient recruitment tools help teams reach broader populations and fill enrollment targets faster.

 

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Getting started

Key features

video play button eRecruitment and patient matching

Ensure eligibility, increase your reach to potential participants, and reduce site and participant burden with pre-screening surveys.

hybrid consent Hybrid eConsent (electronic informed consent) for remote or on-site

Castor’s eConsent (electronic informed consent) solution features built-in video conferencing, so you can provide a high-touch experience while minimizing the distance participants need to travel.

simplify participant data collection Native ePRO (Electronic Patient-Reported Outcomes) app and eCOA (electronic clinical outcome assessments) solution

Increase engagement by providing an enhanced experience for participants and reduce administrative burden by simplifying data collection.

connected wearable device Sensor & wearable integration

Collect real-time biometric data and other digital endpoints with Castor’s robust API and philosophy of interoperability.

worldwide reusable data Integrated EDC (electronic data capture) with seamless integration

Castor’s built-in Integrated EDC (electronic data capture) system makes it easier to deploy studies faster, capture real-world trial data, and integrate it seamlessly with other data in your ecosystem.

upload cloud API and Interoperability

Minimize SDV procedures and data error while eliminating your need for duplicate documentation.

Everest Group’s PEAK Matrix® of Decentralized Clinical Trials Products Assessment 2021

Delivering shorter build-times and seamless integration

Clinical trials succeed when data flows. That’s why Castor is reengineering traditionally stodgy processes with easy-to-use digital tools that remove barriers for participants and researchers.

See why our company was chosen as a Major Contender impacting the market in the Everest Group’s PEAK Matrix® of Decentralized Clinical Trials Platforms Assessment 2023.

 

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