Electronic Clinical Outcome Assessments (eCOA)

Accelerate Patient-Reported Outcomes (PRO) Collection with Global-Ready, API-First Technology

Castor eCOA / ePRO delivers rapid, compliant, and scalable patient-reported data capture—whether you’re running traditional, hybrid, or fully decentralized trials. As part of Castor’s unified platform or as a standalone solution, eCOA enables sponsors and CROs to streamline the participant experience, ensure data integrity, and power confident clinical decisions.

Built for Global Scale, Proven in Complex Studies

With a footprint spanning 90+ countries, Castor has supported studies in:

Africa, Asia-Pacific, Australia
United States & Canada
Latin America
Europe

We maintain a secure, globally distributed infrastructure that aligns with regional data protection laws and regulatory guidelines, including GDPR, HIPAA, and applicable data privacy laws in APAC, LATAM, and EMEA. Castor supports data localization where required and ensures full compliance with global privacy standards through ISO 27001-certified hosting environments.

Therapeutic Area Experience

Castor eCOA / ePRO has been deployed successfully across high-complexity and high-sensitivity indications. Our experience spans:

Central Nervous System

Pain, addiction, depression, and broader mental health

Rare Disease

Genetically targeted and low-population studies

Oncology

Complex, longitudinal studies with high eCOA volumes

Infectious Disease

Acute and chronic infectious disease, including global surveillance and intervention trials

Cardiovascular and Metabolic

Hypertension, diabetes, and lipid disorders

Immunology & Autoimmune

Rheumatoid arthritis, IBD, Crohns disease, and related inflammatory diseases

These studies often involve vulnerable populations, demanding precise, intuitive, and engaging eCOA solutions—all supported by Castor’s configurable platform and expert services.

Technology That Eliminates Barriers

Castor’s eCOA / ePRO is built on the principles of interoperability, transparency, and speed. Designed for modern trial delivery models, Castor supports:

API-First Architecture

Seamlessly integrate with EDC, IRT/RTSM, recruitment tools, analytics tools, and patient payment platforms

No Data Silos

All eCOA data flows in real-time into Castor’s unified data layer or your preferred system

BYOD Applications

Both web and native mobile apps, with multilingual support, accessibility features, push notifications, SMS messaging, and email delivery

DCT-Ready

Serve patients in-home, onsite, or through hybrid workflows, with offline support and BYOD capabilities

Standalone or Integrated eCOA

Deploy eCOA independently or alongside eConsent, eClinRO, and eObsRO in a coordinated participant experience

Library of Validated Assessments

Access reusable, pre-approved PRO instruments to accelerate study builds and ensure quality

Monitoring and Alerts

Automated system and data monitoring with configurable alerts for study teams and Castor support to preempt potential disruptions.

Global Help Desk

Dedicated multilingual support team with 24/7 availability via chat, email, and phone, and backed by SLA-driven resolution times

Castor’s API-first technology enables the development of eCOA / ePRO solutions that are fit-for-purpose for any protocol—from early-phase proof-of-concept to multinational pivotal studies.

One login,

one database, one audit trail.

Unified by Design

Castor’s eCOA / ePRO is not a separate add-on—it’s natively integrated with our EDC, eConsent, and eCOA platform. All participant data flows seamlessly into a single system in real-time—no third-party syncs, no manual uploads, no fragmented data.

From First Patient In to Last ePRO Submitted - Castor Delivers with Speed and Confidence

Results You Can Trust

1,000+ patients supported in a single study with >95% compliance rate
25,000+ ePROs completed using intelligent delivery via SMS and email, ensuring participants stay engaged
Studies fully deployed in under 8 weeks using reusable templates and low/no-code tools, ensuring accelerated time to value for your clinical trials
Mid-study changes implemented in less than 4 weeks—without disrupting ongoing data capture or introducing compliance risk
Full compliance with 21 CFR Part 11, ICH-GCP, GDPR, HIPAA, and regional frameworks
Security and Quality Systems certified to ISO 27001 and ISO 9001

Why Castor eCOA / ePRO?

Castor combines the innovation of an API-first platform with the practical needs of global trial operations, delivering accelerated time to value through rapid deployment and seamless integration. Whether you’re running a Phase I dose escalation in a single country or a global DCT across 10+ regions, Castor eCOA empowers you to:

Simplify patient engagement
Reduce site burden
Maintain inspection-readiness
Centralize your data ecosystem
Launch faster, with lower TCO

Download the ePRO factsheet

Transform eCOA from an operational challenge into a strategic driver of trial success.

Next Steps Checklist