Run clinical trials at the speed of your science

Traditional eClinical platforms are built for big pharma. Too slow, too expensive, and too complex for a lean team burning cash. Castor is different. We help small biotech teams launch trials in weeks and build the audit-ready data that holds up to FDA review and Series C diligence.

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Trusted by Series A, B, and C biotech teams worldwide

 
 
The biotech clinical ops reality
“Every week your trial sits in setup is runway you’re not getting back.”
“Your data has to survive a due diligence room you don’t control.”
“A four-person clinical team cannot also be a data management department.”
One platform, not four systems

Everything your trial needs in a single validated environment

EDC

Electronic data capture with real-time site oversight

ePRO / eCOA

Patient and clinician outcomes on any device

eConsent

Regulatory-grade consent with full audit trail

Data management

Fixed-fee DM team, zero CRO layer

EDC + eCOA + eConsent

Audit-ready from day one, not from the day before inspection

Your electronic data capture system should enforce data quality continuously, not surface problems at lock. Castor applies ALCOA+ principles at the point of entry: every field has a timestamp, every change has an audit trail, and every site has real-time access to outstanding queries.

  • 21 CFR Part 11 and Annex 11 compliant audit trail on every data point
  • Real-time site oversight and query management dashboard
  • ALCOA+ enforcement at field level, not as a cleanup step
  • eCOA, eConsent, and EDC share a single validated data layer
  • ICH E6(R3) compliant data management workflows
Patient login success rate across eCOA studies
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ALCOA+

Data integrity principles enforced at field level

Part 11

FDA 21 CFR Part 11 compliant across all modules
ePRO that builds your Series C case

Quality-of-life data collected in Phase I becomes valuation evidence in Phase III

Start collecting health economics and outcomes research (HEOR) data from Phase I and II, not Phase III. This evidence base supports HTA and payer discussions at licensing negotiations and strengthens your Series B or C fundraising narrative with data most competitors simply do not have.

  • Patient-reported outcomes on patients’ own devices (BYOD), no provisioning cost
  • Validated instruments across oncology, rare disease, immunology, and more
  • Greater than 92% ePRO compliance rate across biotech studies
  • HEOR-ready data exports compatible with HTA submission formats
  • Multilingual support for international studies from day one
ePRO compliance rate across biotech studies
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BYOD

Patient’s own device supported, no provisioning cost

Phase I+

Start HEOR data collection from first-in-human
Data management without the overhead

A dedicated data management team, fixed fee, no middlemen

Most small biotech teams cannot staff a full clinical data management function in-house. Castor’s fixed-fee data management service gives you a team with an average of 11 years of tenure, acting as a direct extension of your clinical operations. No variable billing, no layers between you and the data.

  • Fixed-fee pricing: predictable costs, no hourly overruns
  • 11-year average DM team tenure: experienced from day one
  • Database build, query management, and data lock delivered end to end
  • Direct access: no CRO layer, no account manager relay
  • Regulatory-grade documentation ready for inspection
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Fixed fee

No variable billing, no overrun surprises

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Intermediate layers between you and your data team

Molecule and modality coverage

Built for the science you're actually doing

Castor runs across molecule types and therapeutic modalities. The same validated platform that powers a 15-patient FIH study handles a 100-patient multi-country Phase III.

Gene therapy

FDA-regulated gene therapy trials across Phase I through Phase III, including multi-country studies with complex dosing and safety reporting requirements.

mRNA and CAR-T

Advanced cell and gene therapies requiring specialized audit trail, cryopreservation logistics tracking, and cross-site data coordination.

mAbs and biologics

Monoclonal antibodies and biologics in oncology, immunology, and inflammatory disease. Supports adaptive designs and biomarker-driven endpoints.

AI diagnostics

Clinical evidence generation for AI-powered diagnostic platforms, including imaging endpoints and real-world validation studies.

Neuromodulation and digital health

Wearable-integrated data collection and decentralized clinical trials for neuromodulation devices and digital therapeutics.

Rare disease and pediatric

Small patient populations, orphan drug designations, and multi-language consent workflows for rare disease and pediatric indications globally.

Castor in biotech

The numbers behind 500+ biotech studies

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After implementing Castor as their PMCF data collection platform, MMI increased study enrollment by 500% while producing the audit-ready documentation required for EU MDR compliance. Castor’s eCRF builder and Professional Services team helped MMI move from protocol design to first patient enrollment significantly faster than their previous approach.

OncoBioMix: one coordinator, one platform, $100,000 saved

OncoBioMix is a founder-led oncology biotech running Phase II studies with a small internal clinical team. Rather than building a full data management function or adding a CRO layer, they used Castor’s fixed-fee data management service and built their trial operations directly in the platform.

A single study coordinator managed the full trial operation. Castor handled database build, query management, and data lock. The result was $100,000 in staffing cost savings without any compromise on data quality or inspection readiness.

“Castor gave us the infrastructure of a big-pharma trial without the headcount of one. Our data is inspection-ready and our team is the same size it was on day one.”

Dr. Michael Liss, OncoBioMix

$100K

Staffing cost savings reported

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Study coordinator managing full trial operations

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CRO or intermediate data management layers
Regulatory readiness

Data that survives FDA review and due diligence

Castor is built to the regulatory standards that matter for a biotech submission. ICH E6(R3) took effect in the EU in July 2025 and in the US in September 2025. Castor’s unified data layer already meets the quality management and data integrity requirements of the updated GCP guidance.

  • ICH E6(R3) compliant quality management and audit trail
  • 21 CFR Part 11 and EU Annex 11 compliance across all modules
  • GDPR-compliant patient data handling for EU studies
  • ISO 27001 certified information security management
  • HIPAA compliant for US-based data
  • FDA 21 CFR Part 820 quality system compliance

Real-world evidence studies and post-market registries follow the same validated infrastructure as interventional trials.

21 CFR Part 11

FDA electronic records and signatures

ICH E6(R3)

Updated GCP compliance, EU and US

ISO 27001

Information security management

GDPR

EU patient data protection

HIPAA

US health data compliance

EU Annex 11

Computerized systems in clinical trials

Common questions from biotech teams

Yes. Castor supports gene therapy, CAR-T, mRNA, mAbs, and rare disease trials across Phase I through post-market. The platform handles complex dosing logic, multi-site coordination, and the audit trail requirements specific to advanced therapy medicinal products regulated by FDA and EMA. Our molecule-agnostic design means the same validated platform works for a 15-patient first-in-human study and a 100-patient multi-country Phase III.

Audit-ready data means every data point has a complete, tamper-evident audit trail from entry to lock: who entered it, when, and what changed. For an FDA submission, this means your 21 CFR Part 11-compliant audit log can be exported and reviewed by an inspector without remediation. Castor enforces ALCOA+ principles at the system level, so audit readiness is built into the data collection process rather than applied as a cleanup step before submission.

ePRO and eCOA data collected in Phase I and II creates a health economics and outcomes research (HEOR) evidence base that supports payer negotiations, health technology assessment submissions, and licensing discussions at Series B or C. Investors and acquirers treat this data as a value signal. Companies that start collecting quality-of-life and patient-reported endpoints early arrive at late-stage fundraising with evidence that most competitors built only in Phase III.

Yes. Castor’s fixed-fee data management service is designed for teams without in-house DM capacity. Our data managers, who average 11 years of tenure, act as an extension of your team: building the database, managing queries, running data quality checks, and delivering clean data for lock. There is no CRO layer and no variable hourly billing. OncoBioMix ran a complete clinical operation with one study coordinator using Castor for data management, reporting $100,000 in staffing cost savings.

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